Liver the largest, most sensitive and vital organ performs many vital functions of the body from facilitation of lipid and glucose metabolism, synthesis of proteins, cholesterol and hormones, to detoxification and excretion of waste. A nutrient store house, with anabolic roles. A major contributor to the immune system, acting as the first barrier to all antigens and a role in controlling immune responses like inflammation and stress.
Liver has a self-repairing nature maintaining its vitality due to the hepatocytic regeneration capacity. This capacity of the liver can be damaged or affected by the continuous and excessive movement of toxic substances through it, affected by dietary imbalance and the too rapid feed transitions. These intense activities lead to accumulation of waste and toxins in the liver. Animals at this juncture show decrease of appetite, reduced bile secretions, increased pancreatic secretions, leading to a deterioration in the absorption and assimilation of the nutrients from the intestine. Resulting in reduction of iron metabolism, red blood cells, fat soluble vitamins, glucose and improper urea and amino acids metabolism. Leading to poor feeding, growth and production.
Hepatitis consequences, a cause of concern in cattle
During periods of stress, feed alone does not suffice to cover all the needs so is forced to use up its reserves to meet it. When this demand is too high, results in Steatosis or Ketosis, the fatty acid accumulation resulting in liver inflammation. Weakening of immune system leading to mastitis, the leucocytes lose ability to migrate and fight against infection, the intestinal barrier also is weakened, thus leading to an insurgence of infections, vitamin deficiencies and can even affect the fertility, since the production of some proteins and hormones is hampered 
Role of Liv Herbs Plus Inositol and Sorbitol
A synergistic and judiciously selected combination of Liv herbs plus Inositol and Sorbitol as coadjuvants with Lipotropic and antioxidant activity, important for liver health and functioning. These herbs, Inositol and Sorbitol are well documented in earlier studies and research for their hepatic and growth enhancing activity.
Aegle marmelos improved digestion, decreased urea and serum cholesterol, potent against dysentery and diarrhea, gut microbial toxin absorption and bacterial and viral adjuvant. Tannins, Flavonoids and Coumarins make it anti-inflammatory, antioxidative, antipyretic and effective preventer of hepato cytotoxicity.
Silybum marianum’s (Milk thistle) antioxidant with oxidative stability, hepatoprotective, Anti-inflammatory, Antifibrotic, supports liver function, detoxification, improves gut micro flora and reduces intestinal disease incidence, helps repair damaged liver cells, helps in cooling the body and hormonal balance.Gynostemma, Terminalia & Tecomella hepato protective, increases biliary secretion and flow, relieve bloating and loss of appetite, enhances animal health and weight.Eclipta alba Schisandra & Goji Berry, anti- hepatotoxic, potentiate feed assimilation and utilization.Picorrhiza kurroa are good stomachic, useful in in-appetence conditions.Citrullus & Zingiber help detoxify and reduce excessive metabolic heat.
Andrographis paniculata –Hepatoprotective, anti-oxidant, detoxifier, relieves indigestion, supports healthy gallbladder, lipid breakdown with healthy flow of bile.Solanum nigrum & Azadirachta indica : antispasmodic, hepatoprotective , antioxidant, antipathogenic.Boerhavia diffusa & Trachyspermum – hepatoprotective, Astringent, cooling, anthelmintic, diuretic, emetic, expectorant.Inositol the natural sugar-alcohol readily absorbed and carried to the muscle improves growth acts as a cell messenger and binding to the neurotransmitter, anti-oxidant, regulating lipid metabolism and hepatic function.Sorbitol – anti-inflammatory, detoxification, supports gallbladder function, bile secretion and hepatic regeneration.
Summarized Efficacy of Liv Herbs plus Inositol and Sorbitol in Cattle
Amelioration of Hepatic lesions, inhibition of lipoperoxidation that causes cellular membrane damage, hepato protective, regenerative and anti-oxidant activity, with reduced hepato megaly. Inhibiting the toxic ethanol, carbon tetra chloride, acetaminophen formation. Enhanced hepatic glutathione production with increased protein synthesis in hepatocytes.
MODE OF WORKING
The working of phytochemicals of Liv Herbs plus Inositol and Sorbitol as per studies conducted by Advance Aqua Bio Technologies India Private Limited, showed that the Gut microbes of cow fed with Liv herbs plus Inositol and sorbitol blend, metabolized feed starch into volatile fatty acids, lactates and propionates, broken down to glucose, for energy, this negative energy balance leads the body to utilize fat as energy source. The liver enzymes convert this fat into usable energy. The harmful toxic substances converted to their inert forms. Reduced Beta-hydroxy-butyric acid, indicates good liver health, better fat oxidation, reduced free radicals and competitive inhibition.
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